Association between MTHFR C677T polymorphism and folate, vitamin B12, homocysteine, and DNA fragmentation in patients with ovarian cancer.

Autor: Özkılıç, Anıl Çağla, Çetin, Ahmet, Bayoğlu, Burcu, Balcı, Huriye, Cengiz, Müjgan
Předmět:
Zdroj: Turkish Journal of Biochemistry / Turk Biyokimya Dergisi; Dec2016, Vol. 41 Issue 6, p459-465, 7p
Abstrakt: The article discusses a study which assessed the correlation between reductase (MTHFR) C677T (rs1801133) polymorphism and homocysteine, vitamin B12, and folate levels, and DNA fragmentation in patients with ovarian cancer. Topics covered include findings which showed that there is no association between MTHFR C677T polymorphism and ovarian cancer, and that patients with ovarian cancer had increased DNA fragmentation.
Databáze: Complementary Index