Pardon the Interruption: A Modification of Fischer’s Venerable Reaction for the Synthesis of Heterocycles and Natural Products.

Autor: Susick, Robert B., Morrill, Lucas A., Picazo, Elias, Garg, Neil K.
Předmět:
Zdroj: Synlett; 2016, Vol. 28 Issue 1, p1-11, 11p, 16 Diagrams, 2 Charts
Abstrakt: This account provides an overview of our laboratory’s studies of an unusual variant of the Fischer indolization reaction. We describe the discovery of the so-called ‘interrupted Fischer indolization’ and the development of the reaction from a methodological standpoint. In addition, our efforts to evaluate and apply this methodology in the context of akuammiline alkaloid total synthesis are discussed. 1 Introduction 2 Interrupted Fischer Indolization Methodology 3 Applications in Akuammiline Alkaloid Total Synthesis 4 Concluding Thoughts [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index