Serum Retinol Levels in Pregnant Adolescents and Their Relationship with Habitual Food Intake, Infection and Obstetric, Nutritional and Socioeconomic Variables.

Autor: Spíndola Garcêz, Laís, de Sousa Paz Lima, Geania, de Azevedo Paiva, Adriana, Sampaio da Paz, Suzana Maria Rebêlo, Lázaro Gomes, Erica Ivana, Sutti Nunes, Valéria, Cotta de Faria, Eliana, de Barros-Mazon, Sílvia
Zdroj: Nutrients; Nov2016, Vol. 8 Issue 11, p669, 11p
Abstrakt: Globally, vitamin A deficiency (VAD) affects about 19.1 million pregnant women. Its occurrence is classically associated with inadequate food intake and may also be associated with socioeconomic factors and the presence of infection. The aim of this study was to determine the factors related to serum retinol levels among pregnant teenagers. The sample consisted of 89 pregnant adolescents, from whom socioeconomic, obstetric, anthropometric, and food consumption data were collected. Serum concentrations of retinol and the supposed presence of infection were determined by high-performance liquid chromatography and C-reactive protein quantification, respectively. The serum retinol concentrations were classified according to the criteria of the World Health Organization. We adopted a 5% significance level for all statistical tests. Serum retinol levels were significantly and positively associated with sanitation (p = 0.008) and pre-gestational nutritional status (p = 0.002), and negatively with the trimester (p = 0.001). The appropriate sanitation conditions and pre-pregnancy body mass index (BMI) were shown to have a protective effect against VAD. Conversely, serum retinol levels were reduced with trimester progression, favoring VAD occurrence. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index