| Autor: |
Blake, Robert S., Ouheda, Saleh A., Evans, Corey J., Monks, Paul S. |
| Předmět: |
|
| Zdroj: |
Analyst; 12/21/2016, Vol. 141 Issue 24, p6564-6570, 7p |
| Abstrakt: |
Alkanes provide a particular analytical challenge to commonly used chemical ionisation methods such as proton-transfer from water owing to their basicity. It is demonstrated that the fluorocarbon ions CF3+ and CF2H+, generated from CF4, as reagents provide an effective means of detecting light n-alkanes in the range C2–C6 using direct chemical ionisation mass spectrometry. The present work assesses the applicability of the reagents in Chemical Ionisation Mass Spectrometric (CI-TOF-MS) environments with factors such as high moisture content, operating pressures of 1–10 Torr, accelerating electric fields (E/N) and long-lived intermediate complex formation. Of the commonly used chemical ionisation reagents, H3O+ and NO+ only react with hexane and higher while O2+ reacts with all the target samples, but creates significant fragmentation. By contrast, CF3+ and CF2H+ acting together were found to produce little or no fragmentation. In dry conditions with E/N = 100 Td or higher the relative intensity of CF2H+ to CF3+ was mostly less than 1% but always less than 3%, making CF3+ the main reagent ion. Using O2+ in a parallel series of experiments, a substantially greater degree of fragmentation was observed. The detection sensitivities of the alkanes with CF3+ and CF2H+, while relatively low, were found to be better than those observed with O2+. Experiments using alkane mixtures in the ppm range have shown the ionisation technique based on CF3+ and CF2H+ to be particularly useful for measurements of alkane/air mixtures found in polluted environments. As a demonstration of the technique's effectiveness in complex mixtures, the detection of n-alkanes in a smoker's breath is demonstrated. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
