| Autor: |
De Ruiter, Anne J. H., Koolhaas, Jaap M., Keijser, Jan N., Van Oortmerssen, Geert A., Bohus, Bela |
| Předmět: |
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| Zdroj: |
Aggressive Behavior; 1992, Vol. 18 Issue 2, p149-157, 9p |
| Abstrakt: |
In this study, testosterone secretory capacity of testicular Leydig cells during ontogeny was determined In males of an aggressive and a non aggressive genetic selection line of wild house mice. Neonates, 23-day-old prepubertals, and adult male mice were studied. A morphometric method was used to quantify 3β-hydroxy steroid dehydrogenase (3β- HSD)-stained Leydig cells in testicular sections to determine testosterone secretory capacity. We consider this parameter to reflect circulating testosterone in the plasma. The results of this study show that the testosterone secretory capacity of Leydig cells in the testis changes differentially during development In males of the aggressive and non-aggressive selection lines. This capacity of highest in the aggressive selection line males at adulthood and at the prepubertal age of 23 days. Surprisingly, at birth, the highest T-secretory capacity was observed in the mates of the non aggressive selection line. The significance of an interaction between genetic factors and differences in perinatal testosterone for the individual variation in adult aggressive behavior is discussed. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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