Comparison of Efficacy and Safety of Intramuscular Piroxicam and Tramadol for Post-operative Pain in Patients Undergoing Caesarean Delivery.

Autor: THIPPESWAMY, TEJASHREE, KRISHNASWAMY, BHUVANA, BENGALORKAR, GIRISH M., MARIYAPPA, NARAYANASWAMY
Předmět:
Zdroj: Journal of Clinical & Diagnostic Research; Nov2016, Vol. 10 Issue 11, p1-4, 4p
Abstrakt: Introduction: Post-caesarean section pain can be both stressful and unfavourable. Effective and rapid reduction of pain facilitates early ambulation and care of the new born. Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) and opioids are used for pain relief but they are associated with adverse effects both in the mother and the child. Aim: To evaluate efficacy and safety of piroxicam and tramadol in post-caesarean section pain. Materials and Methods: Primigravidae who underwent elective caesarean section received either piroxicam 20mg or tramadol 100mg intra-muscularly, following recovery from anaesthesia. Severity of pain was assessed using Visual Analogue Scale (VAS) and side-effects to study drugs were noted. Rescue analgesic butorphanol 2mg was administered if VAS score was more than four. Patient's satisfaction score was assessed at 12 hours post-operatively. Results: Mean age in piroxicam and tramadol groups were 23.32±3.43 and 22.03±2.0 years respectively. Significant reduction in pain was observed at 2, 4, 8, 12 and 24 hours in both groups (p<0.001). Pain relief was significant at 2, 4 and 8 hours in piroxicam group compared to tramadol. Twenty-one and 12 patients in tramadol and piroxicam groups received rescue analgesic respectively. Sedation and nausea was significantly higher in tramadol group (p<0.001), 46.66% of patients graded their satisfaction score as good and 15% as excellent in piroxicam group. Conclusion: Intra-muscular piroxicam was effective in reducing post-caesarean section pain for 24 hours with minimal sideeffects compared to tramadol. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index