The Driving Force for 2014 Dengue Outbreak in Guangdong, China.

Autor: Li, Ming-Tao, Sun, Gui-Quan, Yakob, Laith, Zhu, Huai-Ping, Jin, Zhen, Zhang, Wen-Yi
Předmět:
Zdroj: PLoS ONE; 11/18/2016, Vol. 11 Issue 11, p1-19, 19p
Abstrakt: Dengue fever has rapidly spread in recent decades to become the most globally expansive viral vector-borne disease. In mainland China, a number of dengue outbreaks have been reported since 1978, but the worst epidemic in decades, involving 45230 cases and 76 imported cases, resulting in six deaths in Guangdong province, emerged in 2014. Reasons for this ongoing surge in dengue, both imported and autochthonous, are currently unclear and demand urgent investigation. Here, a seasonally-driven dynamic epidemiological model was used to simulate dengue transmission data recorded from the unprecedented outbreak. Sensitivity analysis demonstrate that delayed mosquito control, the continuous importations between the end of April to the early of July, the transmission of asymptomatic dengue infections, and the abnormally high precipitation from May to August might be the causal factors for the unprecedented outbreak. Our results suggested that the earlier and more frequent control measures in targeting immature and adult mosquitoes were effective in preventing larger outbreaks, and enhanced frontier health and quarantine from the end of April to the early of July for international communications and travelers. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index