| Autor: |
Lodi, Andrea, Betti, Roberto, Chiarelli, Giovanni, Urbani, Carlo Enrico, Crosti, Carlo |
| Předmět: |
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| Zdroj: |
Contact Dermatitis (01051873); Jan1992, Vol. 26 Issue 1, p17-21, 5p |
| Abstrakt: |
We have studied a group of 104 patients with pompholyx. to investigate the relationship between allergotogical factors and its etiopathogenesis, The following examinations were performed, blood sampling routine tests and IgE levels. allergological tests (patch, prick. intradennal. and oral renovation tests with nickel sulphate), skin biopsy to exclude pemphigus vulgarism or bullous pemphigoid. An accurate history of familial and personal allergic diathesis was enquired for and various possible aggravating factors (season. microclimate, perspiration and emotional stress) were considered. The results were age `and sex-matched with a healthy control group (208 Subjects). We found familial and personal atopic diathesis in 50% of patients versus 11.5% of controls (P < 0.001); 39 positivity on patch testing 20.19% versus 6.25% of the control group (P<0.001) the % of Patients allergic to nicked reached 26% meluding those (6 Patients) reacting to the oral propagation test season 143 patients) and hyperhidrosis (38) were the aggravating factors most commonly claimed. We detected no correlation between age, sex, grading of pompholyx, and the allergological parameters investigated. Though several different allergological findings have previously been reported indydhidroiss their role in its pathogenses has not yet been fully explained. We think that different haptens or antigens can produce the same clinical and histological picture of pompholyx in predisposed subjects [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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