| Autor: |
Onajobi, Ismail B., Adhikari, Achyut, Hussain, Shabbir, Javaid, Kulsoom, Fagade, Obasola E., Oladosu, I. A. |
| Zdroj: |
Natural Product Research; Nov2016, Vol. 30 Issue 22, p2507-2513, 7p |
| Abstrakt: |
Two new 10-hydroxy-9(10H)-anthracenone, madagascenone A(1)and B(2),were isolated from the barks ofHarungana madagascariensisLam. The structures of the compounds were determined using 1D- and 2D-NMR and mass spectroscopic techniques. Both of the compounds showed anin vitroα-glucosidase inhibition with IC50 = 69.9 ± 4.21 and 122.3 ± 1.13 μM, respectively, more potent than the standard acarbose (IC50 = 840 ± 1.23 μM). [ABSTRACT FROM PUBLISHER] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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