| Autor: |
Berger, C. L., Edelson, R. L. |
| Předmět: |
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| Zdroj: |
Journal of Cutaneous Pathology; Dec83, Vol. 10 Issue 6, p467-478, 12p |
| Abstrakt: |
Cutaneous T-cell lymphoma is a malignancy of helper T-cells with marked affinity for epidermal tissue. The disease may arise in the skin through neoplastic transformation of normal helper T-cells that naturally migrate through the epidermis. The transformed T-cell divides, forming a clone of malignant helper T-cells that initially retain the characteristics of their normal T-cell ancestor including phenotype, function, and homing pattern. As the disease progresses, more malignant progeny might arise, expressing altered surface antigens and loss of affinity for the epidermis. |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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