Comparision of efficacy of local administration of contractubex & corticosteroids for hypertrophic scar in maxillofacial region.

Autor: Mohan, Muralee, Prasad, B. Rajendra, Sharma, S. M., Shetty, Tripthi, Shah, Ashay
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Zdroj: Nitte University Journal of Health Science; Sep2016, Vol. 6 Issue 3, p16-20, 5p
Abstrakt: Hypertrophic scarring following surgical procedures & trauma are a great concern for patients and a challenging problem for clinicians. The therapeuticmanagement of hypertrophic scars is a problemthat has not yet been satisfactorily solved. Contractubex® ointment and intra lesional injection of corticosteroids have been used effectively for treatment and prevention of hypertrophic scars. However very few data is available to determine the efficacy of Contractubex® ointment and intra lesional injection of corticosteroids for the treatment of hypertrophic scar. Two study groups were made with 10 patients in each group. Patients in Group 1 treated with Contractubex® and patients in Group 2 treated with intra lesional corticosteroid (Triamcinolone acetonide). Scarwas analyzedwith Vancouver Scar Scale (VSS) at 2weeks, 6weeks and 12weeks. The collected datawas statistically analyzed. We found that the difference between before and after treatment scores for each of the groups was statistically significant (p < 0.05). The mean of the before and after treatment difference for the Group 1 (Contractubex®) was 4.7 while that of group 2 (Corticosteroids) was 2.8. This demonstrated a significant superiority of the Contractubex® treatment compared to corticosteroid treatment. The difference between treatment responses for both the groupswas statistically significant (p < 0.05). Excellent to good responses were reported in 90% of the Group 1 (Contractubex®) patients and 30%ofGroup 2 (Corticosteroids). [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index