Oxidative stress parameters and serum magnesium levels in patients with seasonal allergic conjunctivitis.

Autor: Dadaci, Zeynep, Oncel, Mufide, Oncel Acir, Nursen, Sahin, Emel, Borazan, Mehmet
Předmět:
Zdroj: Cutaneous & Ocular Toxicology; Dec2016, Vol. 35 Issue 4, p270-274, 5p
Abstrakt: Objective: To evaluate oxidative stress parameters and serum magnesium (Mg) levels in patients with seasonal allergic conjunctivitis (SAC) during the pollen season. Methods: This observational cross-sectional study involved 35 patients with SAC without any other ocular and systemic diseases, and 38 consecutive, age- and sex-matched healthy subjects. Serum malondialdehyde (MDA), adjusted ischemia modified albumin (IMA), and Mg levels were quantified, and the results were compared between the groups. Results: No significant differences were found between the groups with respect to age (p = 0.416) and sex (p = 0.362). Serum MDA and adjusted IMA levels of the subjects with SAC (69.54 ± 7.71 μM and 0.74 ± 0.39 ABSU) were significantly higher than the control group (64.61 ± 5.89 μM and 0.57 ± 0.19 ABSU) (p = 0.002 andp = 0.025, respectively). There was no significant difference for serum Mg levels between the groups (p = 0.177). Conclusion: We demonstrated higher levels of oxidative stress parameters in patients with SAC compared to the control group, which imply a possible role of oxidative stress in the pathogenesis of SAC. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index