| Autor: |
Dung, Hoang Viet, Bach, Nguyen Van, Trung, Trinh Nam, Nhiem, Nguyen Xuan, Tai, Bui Huu, Kiem, Phan Van, Park, SeonJu, Lee, Taek Hwan, Kim, Sun Yeou, Kim, Seung Hyun |
| Zdroj: |
Helvetica Chimica Acta; Sep2016, Vol. 99 Issue 9, p681-686, 6p |
| Abstrakt: |
Using various chromatographic methods, three new megastigmane glycosides, docynicasides A - C ( 1 - 3) and ten known, (6 S,9 R)-vomifoliol 9- O- β- d-xylopyranosyl-(1′′→6′)- O- β- d-glucopyranoside ( 4), hyperin ( 5), quercitrin ( 6), quercetin 3- α- l-arabinofuranoside ( 7), naringenin 7- O- β- d-glucopyranoside ( 8), phloridzin ( 9), phloretin 2′- O- β- d-xylopyranosyl-(1→6)- β- d-glucopyranoside ( 10), pinosylvin 3- O- β- d-glucopyranoside ( 11), tormentic acid ( 12), and chlorogenic acid methyl ester ( 13) were isolated from the fruits of Docynia indica. Their chemical structures were elucidated by physical and chemical methods. All the isolated compounds were evaluated for the inhibitory activity on NO production in LPS-stimulated BV2 cells. As the results, compounds 3 - 5 showed significant inhibitory activity on LPS-stimulated NO production in BV2 cells with the IC50 values ranging from 21.0 to 29.3 μ m. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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