| Autor: |
Fasih, T. W., Sakr, T. M., Ayoub, R. R., Amin, M. |
| Předmět: |
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| Zdroj: |
Separation Science & Technology; 2016, Vol. 51 Issue 13, p2115-2121, 7p |
| Abstrakt: |
In the presented work, nano-crystalline titania (TiO2) was synthesized and evaluated as a novel chromatographic sorbent for the preparation of the medical99Mo/99mTc generator. TiO2was synthesized by dissolving TiCl4.6H2O with isopropyl alcohol to form a semisolid mass that was extensively dried and washed. The physicochemical parameters and surface area of the synthesized nano-crystalline TiO2were evaluated. TiO2was packed as a chromatographic column to study the sorption of99Mo-polymolybdate (VI) anionic solution by dynamic equilibrium. The maximum sorption capacity of99Mo was ~141±2mg Mo/g TiO2, thereby confirming its suitability for using low specific activity99Mo for the preparation of99Mo/99mTc generator. The elution performance of the prepared99Mo/99mTc generator based on Ti-99Mo was evaluated. It showed high radiochemical purity (≥ 97% TcO4−), high radionuclidic purity (≥ 99.99%99mTc) and high chemical purity; all of these specifications show the suitability for use in nuclear medicine applications. [ABSTRACT FROM PUBLISHER] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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