Effects of novel maleimide derivatives on cell cultures with different properties.

Autor:	Ostrovska, Galyna, Maslova, Olga, Delev, Delian, Opatrilova, Radka, Kuzliak, Peter, Savytska, Nataliia
Předmět:	CELL culture CELL lines CELL physiology CELLS CONNECTIVE tissue cells EPITHELIAL cells FIBROBLASTS INORGANIC compounds STEM cells UMBILICAL cord
Zdroj:	Cell & Tissue Banking; Sep2016, Vol. 17 Issue 3, p505-515, 11p
Abstrakt:	The paper is focused on pilot study of effects of novel synthetic protein kinase inhibitors-maleimide derivatives in different concentrations on normal, transformed and multipotent cell lines. Influence on cell proliferation and morphological characteristics has been demonstrated. The chosen agents cause antiproliferative effect on transformed cells and are not cytotoxic to normal cell lines. Moreover, different maleimide derivatives' effects on multipotent cells in attached and floating states has been shown. Described results can be used for further research of the maleimide derivatives as antitumor agents. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
Externí odkaz:	Zobrazit plný text záznamu Full text from SpringerLink