Orthogonally Reacting Boron Coupling Reagents: A Novel Multicomponent- Multicatalytic Reaction [(MC)²R] of Dichlorovinylpyrazine.

Autor: Rebelo, Jordan M., Kress, Steffen, Friedman, Adam A., Lautens, Mark
Předmět:
Zdroj: Synthesis; 2016, Vol. 48 Issue 19, p3155-3164, 10p
Abstrakt: The results presented herein illustrate the feasibility of two orthogonally reacting boron coupling reagents as a new control strategy in multicomponent-multicatalytic reaction [(MC)2R] chemistry. A process employing dichlorovinylpyrazine merging the rhodium-catalyzed hydroarylation with the Suzuki coupling has been discovered. Three new bonds are formed in a one-pot, one-step process efficiently providing highly substituted diaza-dihydrodibenzoxepine products. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index