| Autor: |
Schuler, M.K., Hornemann, B., Pawandenat, C., Kramer, M., Hentschel, L., Beck, H., Kasten, P., Singer, S., Schaich, M., Ehninger, G., Platzbecker, U., Schetelig, J., Bornhäuser, M. |
| Předmět: |
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| Zdroj: |
European Journal of Cancer Care; Sep2016, Vol. 25 Issue 5, p839-848, 10p |
| Abstrakt: |
It has been demonstrated that physical exercise benefits younger patients undergoing allogeneic haematopoietic stem cell transplantation (allo- HSCT). We designed a prospective pilot study investigating whether elderly patients (>60 years) would also be able to participate in such a programme. It consisted of physiotherapist-supervised alternating endurance and resistance workouts on 6 of 7 days a week. Sixteen consecutive patients undergoing allo- HSCT were enrolled into the study. The median age was 64.5 years. Twelve patients participated in the programme until the time of discharge (75%) from the transplant unit. Therefore, the predefined criteria regarding feasibility were met. The reason for drop out was transplantation associated mortality in all patients ( n = 4). Adherence was very good with a median of 85% attended training sessions. No adverse events were recorded. The endurance capacity dropped by 7% and lower extremity strength improved by 2% over time. Quality of life decreased during the study period, with global health being significantly worse at the time of discharge. In conclusion, a combined and intensified strength and endurance exercise programme is feasible and safe in a population of elderly patients undergoing allo- HSCT. Further research should focus on exploring effect sizes of such an intervention by conducting randomised controlled trials. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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