Promotion of 1,3-dipolar cycloaddition between azides and β-enaminones by deep eutectic solvents.

Autor: Martins, Marcos Antonio Pinto, Paveglio, Guilherme Caneppele, Rodrigues, Leticia Valvassori, Frizzo, Clarissa Piccinin, Zanatta, Nilo, Bonacorso, Helio Gauze
Předmět:
Zdroj: New Journal of Chemistry; Jul2016, Vol. 40 Issue 7, p5989-5992, 4p
Abstrakt: A simple procedure to obtain 4-acyl-1-substituted-1,2,3-triazoles, using a deep eutectic solvent (DES), ChCl and ethylene glycol at a 1 : 2 ratio, as the reaction medium is described. The products were obtained in high selectivity and good yields (70–84%). The advantages of the method include easy work-up, metal-free conditions, inexpensiveness, and the ability to be used four times without a loss in yield. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index