| Autor: |
Tambo, F. F. Mouafo, Dahoun, S., Kamadjou, C., Makon, A. S. Nwaha, Fossi, G., Andze, O. G., Sosso, M. A., Mure, P. Y., Mouafo Tambo, F F, Nwaha Makon, A S |
| Předmět: |
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| Zdroj: |
African Journal of Paediatric Surgery; Jul-Sep2016, Vol. 13 Issue 3, p145-149, 5p, 15 Color Photographs |
| Abstrakt: |
Unlabelled: Mixed gonadal dysgenesis is characterised by unilateral chromosomal abnormality, which is probably the result of anaphase lag during mitosis. The 45, XO/46, XY karyotype is the most common form of mosaicism involving the Y chromosome. It is a rare clinical entity with a worldwide incidence of 1.5/10,000 live births. Its epidemiology in Sub-Saharan Africa is not known. This study reports experience in the management of 3 cases at the Yaounde Gynecologic-Obstetric and Paediatric Hospital. From November 2009 to November 2014, 3 cases were successfully managed at our institution.Results: All patients presented with asymmetrical gonadal differentiation. On one side of the body, a poorly-developed testicular gonad and on the other side a gonadal streak. A persistent Mόllerian remnant was equally found in the 3 cases. Management of mixed gonadal dysgenesis should be done in tertiary health care centres. A multidisciplinary team approach is recommended. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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