VEB-1 Extended-spectrum beta-lactamase-producing Acinetobacter baumannii, France.

Autor: Naas, Thierry, Coignard, Bruno, Carbonne, Anne, Blanckaert, Karine, Bajolet, Odile, Bernet, Claude, Verdeil, Xavier, Astagneau, Pascal, Desenclos, Jean-Claude, Nordmann, Patrice, French Nosocomial Infection Early Warning Investigation and Surveillance Network
Předmět:
Zdroj: Emerging Infectious Diseases; Aug2006, Vol. 12 Issue 8, p1214-1222, 9p
Abstrakt: VEB-1 extended-spectrum beta-lactamase-producing Acinetobacter baumannii was responsible for an outbreak in hospitals in France. A national alert was triggered in September 2003 when 4 hospitals reported clusters of A. baumannii infection with similar susceptibility profiles. Case definitions and laboratory guidelines were disseminated, and prospective surveillance was implemented; strains were sent to a single laboratory for characterization and typing. From April 2003 through June 2004, 53 hospitals reported 290 cases of A. baumannii infection or colonization; 275 isolates were bla(VEB-1)-positive and clonally related. Cases were first reported in 5 districts of northern France, then in 10 other districts in 4 regions. Within a region, interhospital spread was associated with patient transfer. In northern France, investigation and control measures led to a reduction of reported cases after January 2004. The national alert enabled early control of new clusters, demonstrating the usefulness of early warning about antimicrobial drug resist. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index