Autor: |
Naas, Thierry, Coignard, Bruno, Carbonne, Anne, Blanckaert, Karine, Bajolet, Odile, Bernet, Claude, Verdeil, Xavier, Astagneau, Pascal, Desenclos, Jean-Claude, Nordmann, Patrice, French Nosocomial Infection Early Warning Investigation and Surveillance Network |
Předmět: |
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Zdroj: |
Emerging Infectious Diseases; Aug2006, Vol. 12 Issue 8, p1214-1222, 9p |
Abstrakt: |
VEB-1 extended-spectrum beta-lactamase-producing Acinetobacter baumannii was responsible for an outbreak in hospitals in France. A national alert was triggered in September 2003 when 4 hospitals reported clusters of A. baumannii infection with similar susceptibility profiles. Case definitions and laboratory guidelines were disseminated, and prospective surveillance was implemented; strains were sent to a single laboratory for characterization and typing. From April 2003 through June 2004, 53 hospitals reported 290 cases of A. baumannii infection or colonization; 275 isolates were bla(VEB-1)-positive and clonally related. Cases were first reported in 5 districts of northern France, then in 10 other districts in 4 regions. Within a region, interhospital spread was associated with patient transfer. In northern France, investigation and control measures led to a reduction of reported cases after January 2004. The national alert enabled early control of new clusters, demonstrating the usefulness of early warning about antimicrobial drug resist. [ABSTRACT FROM AUTHOR] |
Databáze: |
Complementary Index |
Externí odkaz: |
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