Efficacy of low-dose cyproterone acetate compared with minocycline in the treatment of acne vulgaris.

Autor: Monk, B. E., Almeyda, J. A., Caldwell, I. W., Green, B., Pelta, D., Leonard, J., Du Vivier, A., Johnson, K., Tolowinska, I.
Předmět:
Zdroj: Clinical & Experimental Dermatology; Sep87, Vol. 12 Issue 5, p319-322, 4p
Abstrakt: A multi-centre controlled trial of low-dose cyproterone acetate (Diane®, Schering Health Care Ltd) compared with minocycline hvdrochloridc (Minocin®, Lederle Laboratories Ltd) in female patients with acne vulgaris has been undertaken. Seventy-eight patients completed the study. Over a 24-week treatment period, Diane and Minocin were found to be equally effective in reducing the lesion count for comedones, papules and pustules, and in the patients' subjective assessment of their skin. No significant changes in weight or blood pressure were found in either treatment group, and the number of patients reportings side-effects was similar. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index