Autor: |
Bettonville, Marie, D'Aria, Stefania, Braun, Michel Y. |
Zdroj: |
European Journal of Immunology; Jul2016, Vol. 46 Issue 7, p1574-1582, 9p |
Abstrakt: |
T-cell metabolism is central to the shaping of a successful immune response. However, there are pathological situations where T cells are rendered dysfunctional and incapable of eliminating infected or transformed cells. Here, we review the current knowledge on T-cell metabolism and how persistent antigenic stimulation, in the form of cancer and chronic viral infection, modifies both metabolic and functional pathways in T cells. [ABSTRACT FROM AUTHOR] |
Databáze: |
Complementary Index |
Externí odkaz: |
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