Trametes versicolor bioactive compounds stimulate Aspergillus flavus antioxidant system and inhibit aflatoxin synthesis.

Autor: Scarpari, M., Parroni, A., Zaccaria, M., Fattorini, L., Bello, C., Fabbri, A. A., Bianchi, G., Scala, V., Zjalic, S., Fanelli, C.
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Zdroj: Plant Biosystems; Aug2016, Vol. 150 Issue 4, p653-659, 7p
Abstrakt: Aflatoxins are bioactive compounds, which are toxic and carcinogenic for humans and animals, and are produced mainly byAspergillus flavusandA. parasiticus. We studied the effect of some bioactive compounds produced into the culture filtrates of the basidiomyceteTrametes versicoloronA. flavusgrowth and aflatoxin synthesis. Some aspects of the mechanism of action of different filtrate fractions were investigated.The results showed that these compounds stimulate the antioxidant system of theAspergillusmycelia by the induction of a transient and modulated oxidative burst (peroxides and superoxide anions formation) perceived by Afyap1 transcription factor.T. versicolorculture filtrate fractions, significantly inhibited aflatoxin biosynthesis (A: 75% and B: 55%) apparently by stimulating endogenous antioxidant system. In conclusion, bioactive compounds present in theT. versicolorfiltrates probably act by modulating the fungal antioxidant system, eventually leading to aflatoxin inhibition.T. versicolorcould represent a novel promising tool to control aflatoxins in foods and feeds. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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