| Autor: |
Baltazar, Pollyana Irene, Da Silva Moura, Laecio, Pessoa, Gerson Tavares, De Sá Rodrigues, Renan Paraguassu, Sanches, Marina Pinto, Das Neves Diniz, Anaemilia, Das Chagas Araújo Sousa, Francisco, Guerra, Porfírio Candanedo, Neves, Willams Costa, Giglio, Robson Fortes, De Jesus Rosa Pereira Alves, Jacyara, De Assis Leite Souza, Francisco, Braga, Juliana Fortes Vilarinho, Alves, Flávio Ribeiro |
| Zdroj: |
Microscopy Research & Technique; Jul2016, Vol. 79 Issue 7, p637-645, 9p |
| Abstrakt: |
Morphological parameters and renal flow were assessed and measured in six clinically healthy dogs with negative serological and parasitological examinations for canine visceral leishmaniasis (CVL) and six dogs with CVL-positive serological and parasitological tests and asymptomatic condition of the disease. Kidney length and diameter were measured and compared with the aorta/kidney ratio. Alterations in flow were measured using the flow velocity (cm/s) and resistance index (RI). Renal function was assessed by serum biochemical examination (urea, creatine, total proteins, albumin, and globulin) and urinalysis. CVL-positive animals presented heterogeneous kidney echotexture, reduced vascular flow, hypoperfusion, lesser visualization of the arcuate arteries, high RI values (1.06 ± 0.28 for the right kidney and 1.10 ± 0.30 for the left kidney), reduced diastolic flow, and high systolic peak. They also presented positive creatine/RI correlation and between the renal artery vascular flow and kidney diameter. Histopathological analysis of CVL-positive animals was compatible and confirmed hemodynamic changes observed by Doppler ultrasound. The findings in the present study showed that Doppler ultrasonography is a valid method to assess and detect alterations in flow in renal pathological processes with kidney vascular damage, as in the case of leishmaniasis, and can help in the diagnosis of animals with this infection. Microsc. Res. Tech. 79:637-645, 2016. © 2016 Wiley Periodicals, Inc. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
Plný text