Cognitive Reserve and Postoperative Delirium in Older Adults.

Autor:	Tow, Amanda, Holtzer, Roee, Wang, Cuiling, Sharan, Alok, Kim, Sun Jin, Gladstein, Aharon, Blum, Yossef, Verghese, Joe
Předmět:	DIAGNOSIS of delirium COGNITION CONFIDENCE intervals LITERACY LONGITUDINAL method ORTHOPEDIC surgery PROBABILITY theory REGRESSION analysis RESEARCH funding SURGICAL complications ELECTIVE surgery LOGISTIC regression analysis SEVERITY of illness index GERIATRIC Depression Scale DATA analysis software DESCRIPTIVE statistics ODDS ratio
Zdroj:	Journal of the American Geriatrics Society; Jun2016, Vol. 64 Issue 6, p1341-1346, 6p, 3 Charts, 1 Graph
Abstrakt:	Objectives To examine the role of cognitive reserve in reducing delirium incidence and severity in older adults undergoing surgery. Design Prospective cohort study. Setting Hospital. Participants Older adults (mean age 71.2, 65% women) undergoing elective orthopedic surgery (N = 142). Measurements Incidence (Confusion Assessment Method) and severity (Memorial Delirium Assessment Scale) of postoperative delirium were the primary outcomes. Predictors included early- (literacy) and late-life (cognitive activities) proxies for cognitive reserve. Results Forty-five participants (32%) developed delirium. Greater participation in cognitive activity was associated with lower incidence (odds ratio = 0.92 corresponding to increase of 1 activity per week, 95% confidence interval ( CI) = 0.86-0.98, P = .006) and severity (B = −0.06, 95% CI = −0.11 to −0.01, P = .02) of delirium after adjustment for age, sex, medical illnesses, and baseline cognition. Greater literacy was not associated with lower delirium incidence or severity. Of individual leisure activities, reading books, using electronic mail, singing, and computer games were associated with lower dementia incidence and severity. Conclusion Greater late-life cognitive reserve was associated with lower delirium incidence and severity in older adults undergoing surgery. Interventions to enhance cognitive reserve by initiating or increasing participation in cognitive activities may be explored as a delirium prophylaxis strategy. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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