| Autor: |
Solomon, I. P., S. A., Oyebadejo, S. I., Ekong, I. E., Asuquo |
| Předmět: |
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| Zdroj: |
International Journal of Pharmaceutical Research & Allied Sciences; 2014, Vol. 3 Issue 4, p16-26, 11p |
| Abstrakt: |
This study was carried out to investigate the contraceptive effect of Citrus aurantifolia vaginal douche on histomorphology of adult female albino Wistar rats. 25 female Wistar rats were divided into 5 groups containing 5 female per cage. 5 male rats were kept for mating. Group 2 and 3 were douched with 100% and 50% lime concentration Citrus aurantifolia respectively for two weeks. Group 4 and 5 were also douched with 100% and 50% Citrus aurantifolia concentration respectively for two weeks and thereafter mated. Group 1 was the control. Groups 1,2 and 3 were sacrificed, and the vagina, uterus and ovary harvested, processed to paraffin sections, cut at 5micron in thickness, stained, observed under light microscope while Groups 4 and 5 were sacrificed before the last day of gestation to determine its contraceptive effect. The results of Groups 2 and 3 showed significant distortions and inflammation of the cells associated of the ovaries, uterus and vagina. Groups 4 and 5 showed atrophy of foetal materials and fibrosis of myometrium. In conclusion, Citrus aurantifolia vaginal douche has deleterious effects on the female reproductive organs and foetal development. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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