| Autor: |
Nicula, Marioara, Dumitrescu, Gabi, Pacala, Nicolae, Stef, Lavinia, Tulcan, Camelia, Dragomirescu, Monica, Bencsik, Ioan, Patruica, Silvia, Dronca, Dorel, Petculescu-Ciochina, Liliana, Simiz, Eliza, Pet, Ioan, Marcu, Adela, Caraba, Ioan |
| Předmět: |
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| Zdroj: |
Scientific Papers: Animal Science & Biotechnologies / Lucrari Stiintifice: Zootehnie si Biotehnologii; 2016, Vol. 49 Issue 1, p168-177, 10p |
| Abstrakt: |
Natural chelators from some natural sources have been shown their detox heavy metals ability in human and animals. So the present study was carried out to histological compare the aspect of kidney tissue of Prussian carp's specimens, subjected to chronic Cd intoxication with and without garlic, cilantro and chlorella dietary supplementation. 150 Prussian carps, with weight of 10-12 g were divided according to the following treatments for 21 days: C (without treatment), E1 (10 ppm Cd into water as CdCl2 x 1/2 H2O), E2 (10 ppm Cd into water+2% lyophilized garlic in feed), E3 (10 ppm Cd into water+2% lyophilized cilantro in feed), E4 (10 ppm Cd into water+2% lyophilized chlorella in feed). The potential protective effect of the three lyophilized products against the impact of cadmium toxicity was evaluated in terms of hystopathological characteristics. For this purpose, fragments of kidney were removed and routinely processed at the end of experimental period and analyzed in light microscopy. A specific QuickPHOTO Micro 2.2 software has been used for the histological study. Tissue alterations were assessed using the histopathological score ranging from - to +++ depending on the degree and extend of lesions: (-) none, (+) mild occurrence, (++) moderate occurrence, (+++) severe occurrence. Cd contamination has definitely affected the kidney, inducing severe damage in its structure as: swelling and hypertrophy of tubules with nuclear deterioration, pyknosis and cariorrexis, nucleus and cytoplasm degeneration, capillary ectasia and congestions. Active compounds from garlic and cilantro powder have shown the most chelating and antioxidant potential, leading to the evident recovery of kidney architecture, while the response at chlorella treatment was less effective than E2 group and without significant difference compared with E3 group. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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