| Abstrakt: |
Background: Phytochemical screening, antimicrobial and antioxidant activities of the hexane, ethylacetate and methanol crude extracts of Senna occidentalis (L.) leaves were studied in this work. The aim of the work is to ascertain the level of antimicrobial and antioxidant properties of different solvent extracts of S enna occidentalis plant. Methods: The preliminary screening of the various extracts was carried out using standard methods and the results revealed the presence of tannins, alkaloids, reducing sugar, phenols, anthraquinones, resins, saponins and glycosides. The antimicrobial screening was carried out using the following organisms; Staphylococcus aureus, Eshericha coli, Bacillus subtilis, Pseudomonas aeruguinosa, Salmonella typhi, Klebsiellae pneumoniae, Candida albicans, Aspergillus niger, Penicillium notatum and Rhizopus stolonifer. The free radical scavenging capacity using hydrogen peroxide was equally determined to evaluate the antioxidant activities of the extracts. Results: The results obtained showed that Senna occidentalis (L.) leaf extracts have interesting pharmacological active compounds with great radical scavenging and antimicrobial effects and as such could be used in ethno medicine for treatment of some infections and ailments. Conclusion: Further investigations on the chemical compositions and possible isolation of active ingredients would be carried out. [ABSTRACT FROM AUTHOR] |
