| Autor: |
Onofrio, Sarah, Vartan, Christine M., Nazario, Mitchell, DiScala, Sandra, Cuevas-Trisan, Ramon, Melendez-Benabe, John |
| Předmět: |
|
| Zdroj: |
Journal of Pain & Palliative Care Pharmacotherapy; Jun2016, Vol. 30 Issue 2, p124-127, 4p |
| Abstrakt: |
Management of complex regional pain syndrome (CRPS) can be challenging. Various pharmacological approaches have produced mixed results. Buprenorphine activates mu-opioid receptors and antagonizes kappa and delta receptors, acts atN-methyl-d-aspartate (NMDA) receptor, and is an orphan-related ligand-1 receptor agonist. It is available in transdermal patches that last for up to 7 days. This report describes two patients with refractory CRPS who were treated with transdermal buprenorphine. The patients experienced approximately 50% reduction in pain intensity scores. Application site rash that occurred was managed with topical steroid spray used before applying the patch. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
