| Autor: |
Amerongen, A. V. Nieuw, Strooker, H., Oderkerk, C. H., Bank, R. A., Henskens, Y. M. C., Schenkels, L. C. P. M., Ligtenberg, A. J. M., Veerman, E. C. I. |
| Předmět: |
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| Zdroj: |
Journal of Oral Pathology & Medicine; May1992, Vol. 21 Issue 5, p203-208, 6p |
| Abstrakt: |
Unstimulated whole saliva samples of 27 indoor epileptic patients were studied on their protein composition using biochemical and immunochemical methods. A number of salivary proteins appeared at least partially to be hydrolyzed. In a number of saliva samples the concentration of carbohydrate-containing isoenzymes of amylase was reduced. In addition, the concentration of the 20 kD glycoprotein EP-GP was reduced by 60%. Sialic acid, the terminal sugar of the glycoproteins and mucins, was released for about 50% and in three salivas even nearly completely. Moreover, sialic acid-and fucose-containing epitopes could hardly be detected by monoclonal antibodies to human salivary mucins. As a consequence of this hydrolytic breakdown the saliva mediated aggregation of two S. sanguis strains had been reduced. In contrast, the aggregation of S. oralis had been maintained. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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