Clinical and histological features of 'mechanic's hands' in a patient with antibodies to Jo-1--a case report.

Autor: Mitra, D., Lovell, C. L., Macleod, T. I. F., Tan, R. S. L., Maddison, P.J.
Předmět:
Zdroj: Clinical & Experimental Dermatology; Mar1994, Vol. 19 Issue 2, p146-148, 3p
Abstrakt: The clinical and histological features of 'mechanic's hands' are described in a patient with polymyositis characterized serologically by antibodies to histidyl tRNA synthetase (Jo-l). Although described in the past in association with polymyositis, these distinctive cutaneous lesions have only recently been associated with the 'anti-synthetase syndrome'. It is becoming apparent that recognition of subsets within the spectrum of polymyositis/dermatomyositis characterized by certain clinical and serological features not only have prognostic significance, but also may provide insights into mechanisms of disease. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index