| Abstrakt: |
Hypertension is a common disease suffered by patients at the inpatient installation of DR. M. Djamil Padang Hospital. Drugs given to these patients may affect the patients' renal function. This study aimed to determine whether the antihypertensive drugs administration has an effect on patient renal function during their stay at the inpatient installation of DR. M. Djamil Padang Hospital. The study was an observational study by using judgment sampling method of prospective data. It was performed from December 2010 to March 2011. A total of 51 hypertensive patients were included in this study. Patient renal function based on their creatinine clearance can be classified into stage I (2 patients), stage II (4 patients), stage III (19 patients), stage IV (8 patients), and stage V (18 patients). There was a decrease in patient renal function for 35.29% during their stay. This might be due to the use of nephrotoxic drugs and drugs which are excreted by kidney greater than 70% such as furosemid/Lasix® (66.66%), ciprofloxacine (7.84%), hydrochlorothiazide (17.65%), ranitidine (1.96%), captopril (41.17%), propanolol (1.96%), allopurinol (1.96%), Aspilets® (3.92%), simvastatin (1.96%), and cefotaxime (3.92%). In summary, special attention should be given to patients receiving drugs which could cause a decrease in renal function in order to prevent the deterioration of patient's quality of life. [ABSTRACT FROM AUTHOR] |
