INCIDENCE AND RISK FACTORS OF OPIOID ADVERSE EFFECTS AMONG PATIENTS UNDERGOING CAESAREAN SECTION.

Autor: JASIM, HANAN HUSSEIN, SYED SULAIMAN, SYED AZHAR, KHAN, AMER HAYAT, ABDULRAZZAQ, HADEER AKRAM, RAJAH, USHAS.
Předmět:
Zdroj: Malaysian Journal of Phamaceutical Sciences; 2015, Vol. 13 Issue 1, p59-59, 2/3p
Abstrakt: Pruritus, nausea and vomiting during caesarean section are very common and unpleasant events. They cause significant distress to the patient and also interfere with surgical procedures. A retrospective study was conducted for 400 patients to determine the incidence of pruritus, nausea and vomiting and identify the risk factors associated with these adverse effects following caesarean section procedure during 18-month periods from January 2013 to June 2014 at Hospital Pulau Pinang (HPP), Pulau Pinang, Malaysia. Assessment of side effects and its risk factors were manually extracted from patient's medical records during the first 48 hour following the caesarean section. Results indicated that 15.6% of patients (n = 62) complained of different medical and therapeutic complications. Pruritus was present in 10.5% (n = 42), nausea and vomiting in 4.3% (n = 17), urinary retention in 0.5 % (n = 2) and hypotension in 0.3% (n = 1) of patients. Multiple logistic-regression analysis identified that: emotional status (anxious) (odds ratio [OR], 6.714; 95% confidence interval [CI95], 1.42-12.61; p = 0.01); caesarean indication (poor progress) (OR, 5.41; CI95, 1.33-24.65; p = 0.019); blood group (AB) (OR, 6.73; CI95, 1.92-10.64; p = 0.001); were found to significantly affect the incidence of pruritus, while caesarean type (elective) (OR, 5.75; CI95, 1.13-3.37; p = 0.017) was found to significantly affect the incidence of nausea and vomiting. Our findings show that emotional status (anxious), caesarean indication (poor progress), blood group (AB) and caesarean type (elective) are the risk factors that should be incorporated into approaches for the prevention and surveillance of opioid's adverse effects after caesarean section. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index