| Autor: |
Caragea, Gina, Forje, Mărgărita, Macovei, Radu, Tudosie, Mihail, Ardelean, Luminiţa, Bumbea, Viorica, Ionică, Mihai |
| Zdroj: |
Balkan Military Medical Review; 2014 Supplement, Vol. 17, p106-106, 1p |
| Abstrakt: |
Metals and metalloids have urinary major route of elimination from the body. In patients with Chronic Kidney Disease (CKD), the elimination of these chemical elements occurs only during dialysis procedure. This can adversely affect patients quality of life if metals or metalloids accumulate in the body and lead to further problems of their health. The authors provide a Graphite Furnace Atomic Absorption Spectroscopy (GF - AAS) method and the results of quantitative determination of copper obtained in a group of patients with CKD in comparison to a normal renal function control group. For every patient patients were collected two blood samples. One before starting the dialysis procedure and another to completion. During the dialysis, procedure was harvested six samples dialyzed at times: zero, 30 min, 1, 2, 3 and 4 hours. There are presented the blood copper concentrations, dynamics and the amount of copper removed during dialysis session and an accurate assessment of defi ciency/excess copper in patients with CKD in comparison than those of the control group. Although the blood copper concentrations at the end of dialysis procedure is lower than at the beginning, this does not differ signifi cantly. The average amount of copper removed by dialysis session is about 10 times higher than the amount 24h patients with normal renal function. GF-AAS is a sensitive, reproducible and relatively low cost price method. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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