Dose Dependence of the Anticoagulant Effect of Intravenously Administered Cellulose Sulfate.

Autor: Drozd, N., Kuznetsova, S., Kalinina, T., Vasilieva, N.
Předmět:
Zdroj: Bulletin of Experimental Biology & Medicine; Apr2016, Vol. 160 Issue 6, p767-770, 4p
Abstrakt: Experiments on rabbits showed that increasing the dose of intravenously administered cellulose sulfate from wheat straw (dynamic viscosity 3.4 cP, sulfur content 14.1%) increased plasma clotting time in some coagulation tests and plasma anticoagulant activity. When cellulose sulfate was administered in the dose of 1 mg/kg, plasma clotting time in the presence of the anticoagulant (5 min after administration) was ~3-fold higher than after saline administration. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index