| Autor: |
Ţăranu, T., Nedelcu, A. H., Stan, C. I., Ciuntu, B., Georgescu, Şt. O., Ciobanu, Delia, Toader, Mihaela Paula, Ţăranu, Tatiana |
| Předmět: |
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| Zdroj: |
Romanian Journal of Functional & Clinical, Macro & Microscopical Anatomy & of Anthropology / Revista Româna de Anatomie Functionala si Clinica, Macro si Microscopica si de Antropologie; 2016, Vol. 15 Issue 1, p80-90, 11p |
| Abstrakt: |
Primary leiomyosarcoma of the inferior vena cava is a rare malignant tumor, potentially aggressive, of vascular origin. Aim: Presentation of a case of extrinsic and intrinsic primary leiomyosarcoma (with extra and intravascular evolution) of the postrenal segment of the inferior vena cava. Case report of a sixty-six years old patient, admitted for pain in the right flank (for about 11 months); ultrasonographic and echo-Doppler exploratipn and histopathology and immunohistochemistry of the tumor sections postoperative.Results: Hypoechogenic formation, solid and homogeneous, with lateral mass effect on the postrenal wall of vena cava (incomplete stenosis with hourglass lumen). Complete tumor excision was performed together with implantation site, while lateral venous reconstruction using saphenous patch angioplasty was performed. The resection sample was covered by a solid pseudocapsule with firm, homogeneous aspect, with no occlusive thrombus, and a „fish-meat” aspect in cross-section and no necrotic, hemorrhagic or degenerative cystic areas. Immunohistochemistry confirmed an extensive extra and intraluminal leiomyosarcoma with 2nd differentiation degree. Cytoplasmic labeling was positive for desmin, vimentin, SMA, CD 31, while tumor cell nuclei were positive for Ki-67 and negative for S100. Following associated chemo and radiotherapy, the patient has shown no local recurrence at 6 months. Conclusion: Primary vascular leiomyosarcoma of the retroperitoneal vena cava require radical surgery and complementary multimodal therapy (however not curative) to ensure comfortable medium and long term survival rates. Continuous surveillance is required to monitor local recurrences and metastasis. [ABSTRACT FROM AUTHOR] |
| Databáze: |
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