| Autor: |
Cirak, Meltem Yalinay, Ozdek, Ali, Yilmaz, Dicle, Bayiz, Unal, Samim, Erdal, Turet, Sevgi |
| Předmět: |
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| Zdroj: |
Archives of Otolaryngology - Head & Neck Surgery; Nov2003, Vol. 129 Issue 11, p1225-1229, 5p |
| Abstrakt: |
Objective: To determine the presence of Helicobacter pylori and, if detected, the prevalence of the CagA gene in adenotonsillectomy specimens by polymerase chain reaction (PCR). Design: A prospective clinical trial. Setting: Tertiary referral center. Patients and Methods: The study population comprised 23 patients who had undergone adenoidectomy, tonsillectomy, or adenotonsillectomy under local or general anesthesia. Helicobacter pylori DNA was extracted from 3-mm-diameter tissue samples obtained from each tonsil and adenoid tissue specimens. The amplifications were performed for the 16S ribosomal RNA (rRNA) and CagA genes of H pylori in the samples of which H pylori DNA was detected. Results: In examining all the samples, 7 (30%) of 23 patients were shown to be positive for H pylori DNA, 5 (71%) of whom also possessed the CagA gene. Conclusions: Tonsil and adenoid tissues may be an ecological niche of the mouth without regard to transient or permanent colonization. Oral-oral transmission may be a possible mode of spread of H pylori. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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