Pregnancy Outcomes in Women with 1-Hour Glucose Challenge Test ≥ 200 mg/dL.
| Autor: | Ankumah, Nana-Ama, Tita, Alan T. N., Biggio, Joseph R., Harper, Lorie M. |
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| Předmět: |
BIRTH injuries
BLOOD sugar monitoring CHI-squared test CONFIDENCE intervals GESTATIONAL age GESTATIONAL diabetes GLUCOSE tolerance tests LONGITUDINAL method EVALUATION of medical care PREECLAMPSIA SHOULDER dystocia T-test (Statistics) LOGISTIC regression analysis DISEASE incidence RETROSPECTIVE studies ODDS ratio DISEASE complications PREGNANCY DIAGNOSIS |
| Zdroj: | American Journal of Perinatology; 2016, Vol. 33 Issue 5, p490-494, 5p |
| Abstrakt: | Objective Many protocols diagnose gestational diabetes mellitus (GDM) solely on a 1-hour glucose challenge test (GCT) ≥ 200 mg/dL. However, pregnancy outcomes in these women compared with women diagnosed with a 3-hour glucose tolerance test (GTT) has not been adequately evaluated. We hypothesize that a 1-hour GCT ≥ 200 mg/dL is associated with worse pregnancy outcomes as compared with a GCT 135 to 199 mg/dL with positive GTT. Study Design A retrospective cohort of singleton pregnancies complicated by GDM. Maternal outcomes included A2DM, preeclampsia, primary cesarean, and failed trial of labor after cesarean. Perinatal outcomes were large/small for gestational age, shoulder dystocia, and birth injury. Groups were compared with t-test and chi-square test, and logistic regression to adjust for confounders. Results A total of 602 women diagnosed with GDM by 1-hour GCT 135 to 199 mg/dL and confirmatory 3-hour GTT (< 200 group) and 225 women diagnosed with 1-hour GCT ≥ 200 alone (≥ 200) were included. The ≥ 200 group had a higher incidence of preeclampsia (16.4 vs. 10.6%) and shoulder dystocia (3.1 vs. 1.0%). Adjusted odds ratio and 95% confidence interval were 1.80 (1.10-2.94) and 5.10 (1.25-20.76), respectively. Conclusion Preeclampsia and shoulder dystocia are more frequent in women with GCT ≥ 200 mg/dL than those with a positive GTT following a GCT of 135 to 199 mg/dL. [ABSTRACT FROM AUTHOR] |
| Databáze: | Complementary Index |
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