| Autor: |
Kitami, Akihiko, Sano, Fumitoshi, Hayashi, Shoko, Suzuki, Kosuke, Uematsu, Shugo, Kamio, Yoshito, Suzuki, Takashi, Kadokura, Mitsutaka, Omatsu, Mutsuko, Kunimura, Toshiaki |
| Předmět: |
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| Zdroj: |
Surgery Today; May2016, Vol. 46 Issue 5, p593-598, 6p |
| Abstrakt: |
Purpose: The purpose of this study was to evaluate the correlation between histological invasiveness and the computed tomography (CT) value and size in pure ground-glass nodules (GGNs) to determine optimal 'follow-up or resection' strategies. Methods: Between 2001 and 2014, 78 resected, pure GGNs were retrospectively evaluated. The maximum diameter and CT value of pure GGNs were measured using a computer graphics support system. Results: All GGNs with a maximum diameter ≤10 mm and CT value ≤−600 Hounsfield units (HU) were considered to be noninvasive lesions, while 21 of 26 (81 %) with a maximum diameter >10 mm and CT value >−600 HU were considered to be invasive lesions. With respect to the correlation between each histological type and pure GGN with a maximum diameter ≤10 mm and CT value ≤−600 HU, the specificity was 90 % and the sensitivity and negative predictive value were both 100 % in atypical adenomatous hyperplasia (AAH), while the specificity was 58 % and the sensitivity and positive predictive value were 0 % in minimally invasive and invasive adenocarcinoma. Conclusion: Pure GGNs with a maximum diameter of ≤10 mm and CT value of ≤−600 HU are nearly always pre-invasive lesions; therefore, surgery should be carefully selected in such patients. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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