| Autor: |
CARUSO, JOHN F., HAMILL, JOHN L., YAMAUCHI, MIKI, COOK, TIM D., MERCADO, DEAN R., GIBB, GEOFF, HIGGINSON, BRIAN K., ELIAS, JEFF, HERNANDEZ, DAN A. |
| Zdroj: |
Journal of Strength & Conditioning Research; Nov2004, Vol. 18 Issue 4, p753-759, 7p |
| Abstrakt: |
Hind-limb-suspended rats incur attenuated bone loss with b2-agonists, and humans note similar changes with concurrent resistance exercise. To examine if the b2-agonist albuterol helps resistance exercise reduce unloading-induced bone loss, human subjects performed 40 days of unilateral limb suspension with their left legs, otherwise refraining from normal ambulatory activity. While performing left leg strength training 3 days·week-1, subjects received a concurrent placebo or albuterol (16 mg·day-1) treatment. Left leg muscle and bone changes were analyzed with 2 × 2 analyses of covariance (ANCOVAs). Mechanical loading values were calculated from workouts and compared using a 2 × 5 analysis of variance (ANOVA) and a Tukey post hoc test. The resistance exercise-albuterol assignment evoked significant (p < 0.05) left leg bone mineral content (BMC) gains (12.24%) after 40 days. During the final unloading days, the resistance exercise-placebo group's mechanical loading data declined (213.91%) significantly (p < 0.05) versus initial values. A resistance exercise-albuterol assignment likely increased BMC by maintaining the mechanical loading stimulus. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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