Efficacy and safety of afatinib in Chinese patients with EGFR-mutated metastatic non-small-cell lung cancer (NSCLC) previously responsive to first-generation tyrosine-kinase inhibitors (TKI) and chemotherapy: comparison with historical cohort using erlotinib.
Autor: | Lee, Victor H. F., Leung, Dennis K. C., Tim-Shing Choy, Ka-On Lam, Pui-Mei Lam, To-Wai Leung, Kwong, Dora L. W., Choy, Tim-Shing, Lam, Ka-On, Lam, Pui-Mei, Leung, To-Wai |
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Předmět: |
ANTINEOPLASTIC agents
DRUG efficacy MEDICATION safety CANCER treatment NON-small-cell lung carcinoma CANCER chemotherapy CHINESE people PROTEIN-tyrosine kinase inhibitors COHORT analysis DISEASES PROTEIN kinase inhibitors CLINICAL trials COMPARATIVE studies EPIDERMAL growth factor HETEROCYCLIC compounds LONGITUDINAL method LUNG cancer LUNG tumors RESEARCH methodology MEDICAL cooperation METASTASIS GENETIC mutation RESEARCH SURVIVAL analysis (Biometry) EVALUATION research TREATMENT effectiveness THERAPEUTICS |
Zdroj: | BMC Cancer; 2/24/2016, Vol. 16, p1-10, 10p, 1 Black and White Photograph, 5 Charts, 1 Graph |
Abstrakt: | |
Databáze: | Complementary Index |
Externí odkaz: |