Inv(4)(p14q27) in a Case with de novo Acute Nonlymphocytic Leukemia.

Autor: Benasayag, Silvia, Arias, Eugenia, Baialardo, Edgardo, Reyes, Myriam, Sapia, Sandra, Bistmans, Alicia, Slavutsky, Irma
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Zdroj: Acta Haematologica; 2002, Vol. 108 Issue 1, p39-42, 4p
Abstrakt: An inversion, inv(4)(p14q27), was found as the sole karyotypic anomaly at diagnosis in the bone marrow cells from a 65-year-old male patient with an M4 acute nonlymphocytic leukemia (ANLL). To our knowledge, the breakpoints observed in this case appear to be different from other inversions of chromosome 4 previously described in ANLL. The patient we described had a poor response to chemotherapy and had a short survival.Copyright © 2002 S. Karger AG, Basel [ABSTRACT FROM AUTHOR]
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