| Autor: |
Z., IQBAL, S. M. R., KAZMI, Z., MAHMOOD, N., YAZDANIE |
| Předmět: |
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| Zdroj: |
Biomedica; Oct-Dec2015, Vol. 31 Issue 4, p303-309, 7p |
| Abstrakt: |
Background and Objectives: Denture induced stomatitis (DIS) is quite common (up to 65%) among complete denture (CD) wearers and is generally associated with candida albicans (CA). The management of candida associated DIS in elderly is complex due to poor compliance on the part of patient. In this in vivo study, Nystatin was incorporated into tissue conditioner (TC) for the treatment of denture induced stomatitis and investigated the effectiveness of this combination against candida albicans. Methods: It was an interventional, quasi experimental study in which tissue conditioner with Nystatin (500,000 units) and without Nystatin was applied on the fitting surface of upper denture. Effect of this medication against candida albicans was observed. Thirty six (36) patients were selected by purposive non-probability sampling. Upper complete denture was divided into right (Rt) and left (Lt) sides for medication. Right side was the control side i.e., tissue conditioner alone was applied while left side was interventional side i.e., tissue conditioner incorporated with Nystatin (500,000 units) was applied. Samples were taken from the palatal mucosa of both sides before the application of the tissue conditioner and 3 days after medication; candida colonies were detected and counted. Results: The reduction in the number of colonies on both sides was significant (p <. 05) but it was highly marked on the interventional side than on the control side. Conclusion: Nystatin (500,000 units) when combined with tissue conditioner was effective against candida albicans and can be an effective treatment in non-compliant DIS patients. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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