Interdisciplinary therapy changes superoxide dismutase activity and adiponectin in obese adolescents: a randomised controlled trial.
| Autor: | Nunes, João Elias Dias, Cunha, Heitor Santos, Freitas, Zulmária Rezende, Nogueira, Ana Maria Caixeta, Dâmaso, Ana Raimunda, Espindola, Foued Salmen, Cheik, Nadia Carla |
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| Předmět: |
TREATMENT of childhood obesity
ANTIOXIDANTS C-reactive protein CARDIOPULMONARY system STATISTICAL correlation EXERCISE EXERCISE tests GROUP psychotherapy HEALTH care teams INFLAMMATION NUTRITION education PROBABILITY theory RESEARCH funding STATISTICS SUPEROXIDE dismutase T-test (Statistics) DATA analysis OXIDATIVE stress TREADMILLS BODY mass index RANDOMIZED controlled trials TREATMENT effectiveness OXYGEN consumption DATA analysis software ADIPONECTIN MANN Whitney U Test |
| Zdroj: | Journal of Sports Sciences; May2016, Vol. 34 Issue 10, p945-950, 6p |
| Abstrakt: | The objective of this study is to evaluate the effect of interdisciplinary therapy in the parameters of the oxidative stress and the anti-inflammatory responses of obese adolescents. We selected 57 participants, who were randomly divided into 2 groups: interdisciplinary therapy group and a control group. After 6 months of intervention, 17 participants of the interdisciplinary therapy group and 8 of the control group returned for re-evaluation. The interdisciplinary therapy group participated in a treatment with 4 weekly sessions of exercise, a weekly group therapy session and a weekly nutritional education session. Blood parameters of oxidative stress and anti-inflammatory response were evaluated. The results demonstrated that there were significant increases in the interdisciplinary therapy group for superoxide dismutase activity (6.56 ± 3.22 to 11.40 ± 7.49) and ferric-reducing antioxidant potential concentration (532.91 ± 106.48 to 573.25 ± 112.57), although adiponectin levels did not reduce (40.9 ± 29.34 to 49.05 ± 41.22). A significant decrease in nitrite levels was also found (14.23 ± 8.48 to 11.45 ± 6.05). In the control group, significant reduction was found in adiponectin (31.56 ± 18.88 to 18.01 ± 11.66). This study suggests that interdisciplinary therapy for 6 months was effective in improving the anti-inflammatory responses and the antioxidant defences in obese adolescents. [ABSTRACT FROM PUBLISHER] |
| Databáze: | Complementary Index |
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