| Autor: |
Das, Shoubhik, Bobbink, Felix D., Bulut, Safak, Soudani, Mylène, Dyson, Paul J. |
| Předmět: |
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| Zdroj: |
Chemical Communications; 2/11/2016, Vol. 52 Issue 12, p2497-2500, 4p |
| Abstrakt: |
The catalytic N-formylation and N-methylation of amines using CO2 as the carbon source represents a facile and sustainable approach for the synthesis of pharmaceuticals and natural products. Herein, we describe highly effective and inexpensive thiazolium carbene-based catalysts derived from vitamin B1 for the N-formylation and N-methylation of amines, using polymethylhydrosiloxane (PMHS) as a reducing agent, which operate under ambient conditions. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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