In Search of the Cochlear Amplifier: New Mechanical and Molecular Tools to Probe Transduction Channel Function.

Autor: Karavitaki, K. Domenica, Indzhykulian, Artur A., Duan-Sun Zhang, Corey, David P.
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Zdroj: AIP Conference Proceedings; 2015, Vol. 1703 Issue 1, p1-4, 4p, 1 Color Photograph, 2 Graphs
Abstrakt: The study of mechanotransduction in cochlear hair cells requires stimulus methods that mimic the in-vivo stimulation. We have developed a new mechanical probe to better mimic the physiological stimulus delivered to cochlear hair cells through the overlying tectorial membrane. We combine these new probes with electroporation to study the contribution of different components of the transduction apparatus. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index