| Autor: |
Fenton, Bradford W., Byrnes, Jenifer N., Schmitt, Jennifer J., Schrop, Elise M., Gothard, M. David, Roulette, G. Dante, McCarroll, Michele L., von Gruenigen, Vivian E. |
| Předmět: |
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| Zdroj: |
Journal of Gynecologic Surgery; Feb2016, Vol. 32 Issue 1, p29-34, 6p |
| Abstrakt: |
Background: Inadequate perioperative pain control can lead to complications, including medical problems and extended length of stay (LOS). Outcomes affected by perioperative analgesia include narcotic use and subjective pain. Objective: This research was conducted to evaluate the effect of intravenous (I.V.) acetaminophen on postoperative opioid consumption by women undergoing hysterectomy via any route. Antiemetic use and postoperative anesthesia care unit (PACU) LOS were also evaluated. Design: This was a retrospective, exploratory analysis with a randomized 1:1 matching selection of subjects by surgical procedure. Materials and Methods: Electronic medical records of 966 women who had hysterectomies between January 1, 2010, and July 1, 2013, by any route were reviewed. The primary outcome was opioid consumption (converted to morphine equivalents). The secondary outcomes were antiemetic dosage, ketorolac dosage, and PACU LOS. Results: Both groups were statistically equivalent for age, marital status, insurance, and body mass index. Routes of hysterectomy were matched between groups. There was a significant reduction ( p = 0.004) in PACU LOS in the acetaminophen (ACT) group (116.5 [± 46.22] minutes), compared to the nonacetaminophen morphine-only (MOR) group (125.7 [± 52.30] minutes). Ketorolac administration was significantly lower ( p < 0.001) in the ACT group (0.3 [± 0.52]) doses versus those of the MOR group (0.1 [± 0.31]). Antiemetic doses were also significantly lower ( p = 0.024); the ACT group needed fewer doses (0.2 [± 0.48]) versus (0.3 [± 0.61]) doses needed in the MOR group. The ACT group received 11.4 mg (± 9.80) of morphine equivalents and the MOR group received 11.2 mg (± 8.83) of morphine equivalents; these doses were also not significantly different. Conclusions: Women who received intraoperative I.V. acetaminophen had significantly less PACU time, ketorolac doses, and antiemetics. (J GYNECOL SURG 32:29) [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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