Independent activation of MAP kinase and MPF during the initiation of meiotic maturation in pig oocytes.

Autor: Ye, J., Flint, A.P.F., Luck, M.R., Campbell, K.H.S.
Předmět:
Zdroj: Reproduction; May2003, Vol. 125 Issue 5, p645-656, 12p, 15 Black and White Photographs, 7 Graphs
Abstrakt: Presents a study to clarify the temporal and causal relationships between mitogen-activated protein (MAP) kinase and maturation-promoting factor (MPF) during meiotic maturation, particularly during the resumption of meiosis. Use of pig oocytes matured synchronously in culture; Analysis of kinase activities; Demonstration that MAP kinase is activated simultaneously with MFP at germinal vesicle breakdown; Indication that its activation is not essential for the activation of MPF nor for the resumption of the first meiosis in pig oocytes.
Databáze: Complementary Index