Early specialist care for diabetes: who benefits most? A propensity score-matched cohort study.

Autor:	Booth, G. L., Shah, B. R., Austin, P. C., Hux, J. E., Luo, J., Lok, C. E.
Předmět:	CARDIOVASCULAR disease prevention DIAGNOSIS of dementia CARDIOVASCULAR disease diagnosis HYPERTENSION TUMOR diagnosis CHRONIC diseases CHRONIC kidney failure DATABASES PEOPLE with diabetes INCOME MEDICAL care EVALUATION of medical care MEDICAL specialties & specialists MYOCARDIAL infarction PATIENTS POPULATION RESEARCH funding COMORBIDITY DATA analysis ACCESS to information ACQUISITION of data
Zdroj:	Diabetic Medicine; Jan2016, Vol. 33 Issue 1, p111-118, 8p, 3 Charts, 1 Graph
Abstrakt:	Aims To examine whether early endocrinologist care reduces the risk of cardiovascular complications among newly diagnosed patients with diabetes of differing complexity. Methods We conducted a population-based propensity score-matched cohort study using provincial health data from Ontario, Canada. Adults (≥ 30 years) diagnosed with diabetes between 1 April 1998 and 31 March 2006 who received endocrinologist care in the first year of diagnosis were matched to a comparison group receiving primary care alone (N = 79 020) based on propensity scores and medical complexity (assigned using information on chronic conditions). Individuals were followed for 3- and 5-year outcomes, including non-fatal acute myocardial infarction or coronary heart disease death (primary endpoint), major cardiovascular events (acute myocardial infarction, stroke) or all-cause death, amputation and end-stage renal disease. Results Among medically complex patients, early endocrinologist care was associated with a lower 3-year incidence of the primary endpoint (hazard ratio 0.89, 95% CI 0.78-1.01) and major cardiovascular events or all-cause death (hazard ratio 0.91, 95% CI 0.85-0.97). These effects persisted after accounting for a higher incidence of end-stage renal disease on follow-up and were greatest in those with ≥ 3 visits to an endocrinologist (primary endpoint: hazard ratio 0.69, 95% CI 0.56-0.86 and 0.61, 95% CI 0.45-0.82, for unadjusted and end-stage renal disease adjusted analyses, respectively). In contrast, no benefit was observed in the non-medically complex subgroup. Overall effects were similar at 5 years. Conclusions Early endocrinologist care is associated with a lower incidence of cardiovascular events and death among newly diagnosed patients with diabetes who have comorbid medical conditions. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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