Tertiary Amine Promoted Aziridination: Preparation of NH-Aziridines from Aliphatic α,β-Unsaturated Ketones.

Autor: Armstrong, Alan, Pullin, Robert D. C., Scutt, James N.
Předmět:
Zdroj: Synlett; 2016, Vol. 27 Issue 1, p151-155, 5p
Abstrakt: trans-NH-Aziridines were prepared from aliphatic α,β-unsaturated ketones using a tertiary amine promoted reaction via in situ generated N,N-ylides. Through use of modified conditions the reaction proved to be applicable for the diastereoselective aziridination of a range of enolisable aliphatic α,β-unsaturated ketones of varying substitution patterns. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index